How do you administer rabies immune globulin?
Rabies immune globulin is injected into a muscle, or directly into or near the wound (animal bite or scratch) that exposed you to the rabies virus. A healthcare provider will give you this injection.
Where do you administer rabies vaccine?
For adults, the vaccination should always be administered intramuscularly in the deltoid area (arm). For children, the anterolateral aspect of the thigh is also acceptable.
When is rabies immunoglobulin administered?
Rabies immunoglobulin for passive immunization is administered only once, preferably within 24 hours after the exposure (on day 0 along with the first dose of anti-rabies vaccine).
Where do you administer HRIG?
The recommended dosage of HRIG is 20 IU/kg body weight for all ages including children. Infiltrate as much of the HRIG as possible into and around the bite wound. Administer the remaining HRIG intramuscularly (IM) at a site distant from the first vaccination site, generally in the quadriceps or deltoids.
How painful is rabies immune globulin?
It will depend on your pain tolerance. During your initial treatment, a health care professional will put human rabies immune globulin in the area where you were bitten. This can be painful and can require quite a bit of medicine being placed in and around the wound site.
Why is rabies immune globulin given?
Human Rabies Immune Globulin (HRIG)
HRIG is administered to previously unvaccinated persons to provide rabies virus neutralizing antibody until the patient responds to vaccination by actively producing virus-neutralizing antibodies.
Is 7 days too late for rabies vaccine?
A patient who was bitten by a bat a few months ago is wondering if it is too late to receive rabies PEP. There is no time limit regarding the administration of PEP after an exposure.
Can I take rabies vaccine after 3 days?
The first dose of the 5-dose course should be administered as soon as possible after exposure. This date is then considered day 0 of the post exposure prophylaxis series. Additional doses should then be administered on days 3, 7, 14, and 28 after the first vaccination.
What happens if you get too much rabies immunoglobulin?
cold symptoms such as stuffy nose, sneezing, sore throat; stomach pain, gas, diarrhea; muscle pain; or. pain, swelling, itching, redness, or a hard lump where the shot was given.
How late can you give rabies immunoglobulin?
If HRIG was not administered when vaccination was begun, it can be administered up to seven days after the administration of the first dose of vaccine. Beyond the seventh day, HRIG is not recommended since an antibody response to the vaccine is presumed to have occurred.
How is rabies immune globulin calculated?
Human Rabies Immunoglobulin (HRIG)- Dosage Determination and Interference With the Active Immune Response. Brief Summary: Dosage of rabies immune globulin was calculated from the victim’s body weight, then the amount of rabies immune globulin would be injected as much as possible to all of the wounds.