Can you have LSIL without HPV?
Background: Although low-grade squamous intraepithelial lesions (LSIL) most often are the result of infection by human papillomaviruses (HPV), a small proportion of women with LSIL have negative HPV tests.
Is all LSIL caused by HPV?
LSIL usually is caused by an HPV infection that often goes away on its own. LSIL stands for low-grade squamous intraepithelial lesion. HSIL—This suggests more serious changes in the cervix than LSIL. It is more likely than LSIL to be linked to precancer and cancer.
What is LSIL without HPV?
Low-grade squamous intraepithelial lesion (LSIL) is a common abnormal result on a Pap test. It’s also known as mild dysplasia. LSIL means that your cervical cells show mild abnormalities. A LSIL, or abnormal Pap result, doesn’t mean that you have cancer. The tissue that covers your cervix is made up of squamous cells.
How common is LSIL Pap?
The prevalence of LSIL among young women has also been shown to fluctuate between 2.5% and 7.7%. In addition, in women with high-risk HPV infection, LSIL regresses more slowly (mean 13.8 months) and progresses more quickly (mean time to HSIL or worse 73.3 months) than in women with other HPV genotypes.
Should I worry about LSIL?
Because LSIL does so often heal on its own, most doctors advocate a less aggressive approach to follow-up rather than treatment. In fact, the ACOG guidelines state that CIN 1/LSIL should not be treated unless it has persisted for more than two years, progresses to CIN 2 or CIN 3, or other medical factors are involved.
Does HPV mean my husband cheated?
HPV persistence can occur for up to 10 to 15 years; therefore, it is possible for a partner to have contracted HPV from a previous partner and transmit it to a current partner. It is also possible the patient’s partner recently cheated on her; research confirms both possibilities.
Can LSIL go away?
LSIL is very common and usually goes away on its own without treatment. HSIL indicates more serious changes.
How did I get LSIL?
They are usually caused by infection with certain types of human papillomavirus (HPV) and are found when a Pap test or biopsy is done. LSILs usually go away on their own without treatment, but sometimes they can become cancer and spread into nearby tissue. LSIL is sometimes called mild dysplasia.
Can LSIL be a false positive?
The study found that 114 Pap smears (False Positive: 85%) of 134 reported by the cytotechnologists and 24 (False Positive: 43%) of 56 cytologies reported by the pathologists as LSIL, were negative for HPV infection determined by HC2 (p<0.00003).
What type of HPV causes LSIL?
Our research showed that HPV 16 is the most common type of virus found in ASCUS and LSIL in 50.5% of cases.
Can LSIL be misdiagnosed?
Conditions that can be mistaken for HSIL on biopsy include early invasive carcinoma, atrophy, squamous metaplasia, transitional metaplasia and reactive atypia.
What percentage of LSIL goes away?
LSIL (Low-grade Squamous Intraepithelial Lesion): This Pap smear report suggests that there are definite changes usually due to infection with HPV. These changes may be called HPV alone, or other cells may be present which are called CIN-1. 80% of these LSIL abnormalities go away within 12mths.
Does LSIL affect fertility?
Treatment does not affect your fertility. If possible, check with your doctor or specialist before becoming pregnant to make sure you are up to date with your screenings.
How long does it take for LSIL to clear?
The bottom line here is that the Pap smear result of LSIL is considered “abnormal” and requires further testing and possibly treatment. But the good news is that in most cases, it clears up on its own within two years.