What do you mean by immunogen?
Immunogen is a stimulus that produces a humoral or cell-mediated immune response, whereas antigens are any substance that binds specifically to an antibody or a T-cell receptor.
Is BSA an immunogen?
Bovine serum albumin as an immunogenic carrier facilitating the development of hapten-specific monoclonal antibodies.
What antigens are immunogens?
We can define an immunogen as a complete antigen which is composed of the macromolecular carrier and epitopes (determinants) that can induce immune response. An explicit example is a hapten. Haptens are low-molecular-weight compounds that may be bound by antibodies, but cannot elicit an immune response.
Is immunogen same as antigen?
An immunogen refers to a molecule that is capable of eliciting an immune response by an organism’s immune system, whereas an antigen refers to a molecule that is capable of binding to the product of that immune response. So, an immunogen is necessarily an antigen, but an antigen may not necessarily be an immunogen.
What makes a good immunogen?
Characteristics of a good antigen include:
The ability to be processed by the immune system. Immunogenic regions that are accessible to the antibody-forming mechanism. Structural elements that are sufficiently different from the host.
What is an example of a hapten?
Hapten is a type of antigen that elicits production of antibodies only when combined with another antigenic molecule, such as immunogen. It can however react with previously existing antibodies. A well known example of a hapten is urushiol, which is the toxin found in poison ivy.
What happens if an immune response is directed against a self antigen?
Autoimmune disease occurs when a specific adaptive immune response is mounted against self antigens. The normal consequence of an adaptive immune response against a foreign antigen is the clearance of the antigen from the body.
Do all antigens cause an immune response?
When an antigen binds to a receptor molecule, it may or may not evoke an immune response. Antigens that induce such a response are called immunogens. Thus, it can be said that all immunogens are antigens, but not all antigens are immunogens.
Is BSA an antigen?
Bovine serum albumin (BSA or “Fraction V”) is a serum albumin protein derived from cows. It is often used as a protein concentration standard in lab experiments.
Bovine serum albumin.
Is human serum albumin immunogenic?
On one hand, most foreign proteins are immunogenic. On the other hand, serum albumin is highly conservative and it has similar structure in different species.