You asked: How do you break the BCG ampoule?


How do you dissolve BCG vaccine?

Currently BCG vaccine is freeze-dried powder and sealed under vacuum in a glass ampoule. The powder has to be diluted with saline water and injected within hrs, which often incurs errors owing to inappropriate opening of the glass ampoule and mishandling of the reconstitution.

How long can you keep an open ampoule of BCG vaccine?

Multi-dose Open Vials

Opened vials of measles, yellow fever and BCG vaccines MUST be discarded at the end of each immunization session or after 6 hours whichever comes first.

Does BCG burst?

The BCG vaccine will cause a small lump to appear at the vaccination site within two to six weeks. When the lump at the vaccination site bursts, the site may ooze for a few weeks and sometimes even longer. It usually heals within around two months, leaving a scar on the site.

Why is BCG given in left arm?

The vaccine is given just under the skin (intradermally), usually in the left upper arm. This is the recommended site, so that small scar left after vaccination can be easily found in the future as evidence of previous vaccination.

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How long does BCG last?

BCG vaccination given to babies and young children provides consistent protection (up to 80%) against severe forms of childhood TB, such as TB meningitis. It can be less effective against TB affecting the lungs in adults. The protection from the BCG vaccine can last up to 15 years.

What temperature should BCG vaccine be kept?

The intact vials of BCG VACCINE should be stored refrigerated at 2–8°C (36–46°F). This agent contains live bacteria and should be protected from direct sunlight.

Which vaccines are easily damaged by freezing?

Some of the most widely used vaccines are freeze-sensitive, including:

  • Diphtheria.
  • Tetanus.
  • Pertussis.
  • Liquid Haemophilus influenzae type b (Hib)
  • Hepatitis B.

What is open vial policy?

Implementation of Open Vial Policy allows reuse of partially used multi dose vials of applicable vaccines under UIP in subsequent session (both fixed and outreach) up to four weeks (28 days) subject to meeting certain conditions and thus reduces vaccine wastage.

At what age is BCG vaccine given?

It is recommended that new borns receive the BCG vaccine as soon as they are discharged from the hospital. If for some reason, they miss the BCG vaccination, they can be given the BCG injection anytime up to 5 years of age. It is essential to follow this BCG vaccine schedule to prevent tuberculosis.

How many doses are in a vial of BCG vaccine?

BCG vaccine comes in vials of 20 infant doses, which should be discarded 4–6 hours after opening.

What if BCG goes subcutaneous?

If the vaccine is accidentally given subcutaneously, which occurs ~5%, the bacillus may infect local tissues and the infection can spread to the regional lymph nodes, causing either suppurative or nonsuppurative lymphadenitis [11,12].

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